Recent Activity
WASP
Panzica Updated Gene Info
WASP
Panzica Updated Alias
NMDP1
Naomi Updated Alias
Recent Papers
Alimenti C, Pedrini B, Luporini P, Jiang Y, Vallesi A (2024) Homo- and hetero-oligomeric protein-protein associations explain autocrine and heterologous pheromone-cell interactions in Euplotes. European journal of protistology 94:126075
PUBMED:38520753

Tang H, Guo S, Xue H, Guo Z, Li Y, Yu Q, Liu Y, Zhou W, Ye S (2024) Antiparasitic efficacy of flavonoids identified from Psoralea corylifolia against Tetrahymena piriformis in guppy (Poecilia reticulate). Veterinary parasitology 328:110167
PUBMED:38518713

Stefanov BA, Ajuh E, Allen S, Nowacki M (2024) Eukaryotic release factor 1 from Euplotes promotes frameshifting at premature stop codons in human cells. iScience 27:109413
PUBMED:38510117

What's New

Tetrahymena Genome Data files

Posted on 2023-09-18 12:54:11 by ciliate-curator

We have revamped the arrangement of files under the Genome Data tab found under the Resources menu on TGD. The last annotation of the Tetrahymena thermophila genome was published in 2020, and was the fifth version of genome files to be released to the community. We have labeled these "v5" in the file handles, to help denote them as the latest genome files, and to distinguish them from previous and future versions. The other three Tetrahymena species hosted at TGD (elliotti, borealis, and malaccensis) were only sequenced and annotated once to date, and are labeled "v1". All other files available at the site are listed by date under "Legacy Files". If you have any questions, please contact us at ciliate-curator@bradley.edu

2023 Ciliate Molecular Biology Meeting

Posted on 2023-04-03 21:43:54 by ciliate-curator

The 2023 Ciliate Molecular Biology Meeting will be held from June 26 to 29, 2023 in Montpellier, France. The early registration and abstract submission deadline is April 15, with late registration extending until May 15.

For questions related to the registration and requesting a letter for your visa application, please send an e-mail to ciliatemeeting@123events.fr.

For more details, please visit the meeting website at: https://www.ciliate-meeting-2023.com/en/

Website updates; new genome browser and BLAST interface

Posted on 2022-11-17 14:45:17 by ciliate-curator

Tetrahymena Genome Database Wiki is currently undergoing scheduled website updates. We have replaced the GBrowse genome browser with JBrowse2 and are using this GMOD software to display the T. thermophila macronuclear and micronuclear genome sequences. We have also created a new BLAST server interface. Several community database edits from the last year will be added back before December 1. The T. malaccensis, T. elliotti, and T. borealis genomes will be displayed in JBrowse2 in the next month.

OxyDB has been updated!

Posted on 2021-10-29 00:24:36 by ciliate-curator

We have made changes to OxyDB to reflect the latest reannotation of the genome. Gene names displayed on OxyDB pages have been changed and now link to the updated genome browser. The previous annotation can still be searched using the BLAST server and legacy GBrowse genome browser.

Special Issue of Microorganisms (ISSN 2076-2607): Ciliates as Model Organisms: From ‘omics’ to Genetics, Ecology and Signaling

Posted on 2021-03-22 00:00:00 by ciliate-curator

This Special Issue is open to reporting all studies on ciliates as model organisms, seeking to understand their genetics, cell biology, biochemistry, evolution, ecological adaptation, and the complex mechanisms of signaling systems, from the genes involved to the changes in gene expression during cell response, and from the structure and involved evolution of signal molecules to the membrane traffic in the cells. The deadline for submission is 31 December 2021. We look forward to receiving your contributions. Prof. Dr. Cristina Miceli Prof. Dr. Adriana Vallesi Guest Editors Dr. Ronald Edward Pearlman Co-Guest Editor

Interactions Methods Paper Published

Posted on 2021-03-22 00:00:00 by ciliate-curator

A new paper on methods to identify protein interactions in Tetrahymena has been published. Functional proteomics protocol for the identification of interaction partners in Tetrahymena thermophila. Congratulations to the authors!

Tetrahymena thermophila macronuclear genome fully completed

Posted on 2020-04-16 00:00:00 by ciliate-curator

We have received an update of the Tetrahymena thermophila genome sequence from researchers at Ocean University of China. The gene pages, BLAST server, and Genome Browser have all been updated accordingly to display these new data. Congratulations to the team involved in this effort!

A publication explaining the new sequences and features has been published:
The completed macronuclear genome of a model ciliate Tetrahymena thermophila and its application in genome scrambling and copy number analyses.
Sheng Y, Duan L, Cheng T, Qiao Y, Stover NA, Gao S.
Sci China Life Sci. 2020;10.1007/s11427-020-1689-4. doi:10.1007/s11427-020-1689-4

Proteomics Review Published

Posted on 2019-05-01 00:00:00 by ciliate-curator

A review of nuclear proteomics results described for Tetrahymena thermophila by Saettone, et al. has been published in the journal Genes. Congratulations to the authors!

DNA elimination model published for Stylonychia

Posted on 2018-06-12 00:00:00 by ciliate-curator

A new model for the identification and elimination of DNA sequences from the developing macronucleus has been published.

Postberg, et al., 27nt-RNAs guide histone variant deposition via ‘RNA-induced DNA replication interference’ and thus transmit parental genome partitioning in Stylonychia.

Congratulations to the authors!