TGD | Gene Details

Identifiers and Description

Gene Model Identifier
TTHERM_00188500

Standard Name
GTP4 ( Glucose Transport Protein 4 )

Aliases
PreTt08600 | 15.m00311 | 3697.m00023

Description
major facilitator superfamily protein

Genome Browser v.2008 (current)

Gene Ontology Annotations

Cellular Component
integral to membrane (IEA) | GO:0016021
Molecular Function
transporter activity (IEA) | GO:0005215
Biological Process
transport (IEA) | GO:0006810

Domains

( TIGR00898 ) cation transport protein
( TIGR00880 ) Multidrug resistance protein
( PF06930 ) Protein of unknown function (DUF1282)
( PF07690 ) transporter, major facilitator family
( PF00083 ) transporter, major facilitator superfamily
( TIGR00879 ) MFS transporter, sugar porter (SP)
( TIGR00791 ) transporter, gluconate:H+ symporter (GntP) family
( TIGR00023 ) acyl-phosphate glycerol 3-phosphate acyltransferase
( TIGR00895 ) MFS transporter, aromatic acid:H+ symporter
( TIGR00883 ) MFS transporter, metabolite:H+ symporter (MHS)

Gene Expression Profile

Tetrahymena Functional Genomics Database: TTHERM_00188500

Homologs (v.2006 protein sequences)

Source Identifier Score Description

ParameciumDB GSPATP00024068001 1.99949202699529e-34 Paramecium tetraurelia GSPATP0
0024068001 protein

PlasmoDB PFB0210c 3.00049235912623e-15 Plasmodium falciparum PFB0210c

IPI(HUMAN) IPI:IPI00003909.1 9.00343533975275e-13 PROT:P11169|ENSEMBL:ENSP00000
075120|REFSEQ:NP_008862|H- INV
:HIT000052155 Tax_Id=9606 Solu
te carrier family 2, facilitat
ed glucose transporter member
3

FlyBase FBgn0033644 4.99791645171023e-12

TAIR AT1G19450 5.99805963605737e-11 integral membrane protein, put
ative / sugar transporter fami
ly protein

ToxoDB 33.m00002 3.00071600924832e-10 Toxoplasma gondii facilitative
glucose transporter, putative

DictyBase DDB0205325 9.99680794909155e-09 JC3V2_0_00237 Putative Na+/myo
-inositol symporter.

SGD YDL194W 9.99680794909155e-09 SNF3 SGDID:S000002353, Chr IV
from 111581-114235, Verified O
RF, "Plasma membrane glucose s
ensor that regulates glucose t
ransport; has 12 predicted tra
nsmembrane segments; long cyto
plasmic C-terminal tail is req
uired for low glucose inductio
n of hexose transporter genes
HXT2 and HXT4"

WormBase Y51A2D.4 9.99510677721488e-07 WBGene00013073 Sugar (and othe
r) transporters

Source	Identifier	Score	Description
ParameciumDB	GSPATP00024068001	1.99949202699529e-34	Paramecium tetraurelia GSPATP0 0024068001 protein
PlasmoDB	PFB0210c	3.00049235912623e-15	Plasmodium falciparum PFB0210c
IPI(HUMAN)	IPI:IPI00003909.1	9.00343533975275e-13	PROT:P11169\|ENSEMBL:ENSP00000 075120\|REFSEQ:NP_008862\|H- INV :HIT000052155 Tax_Id=9606 Solu te carrier family 2, facilitat ed glucose transporter member 3
FlyBase	FBgn0033644	4.99791645171023e-12
TAIR	AT1G19450	5.99805963605737e-11	integral membrane protein, put ative / sugar transporter fami ly protein
ToxoDB	33.m00002	3.00071600924832e-10	Toxoplasma gondii facilitative glucose transporter, putative
DictyBase	DDB0205325	9.99680794909155e-09	JC3V2_0_00237 Putative Na+/myo -inositol symporter.
SGD	YDL194W	9.99680794909155e-09	SNF3 SGDID:S000002353, Chr IV from 111581-114235, Verified O RF, "Plasma membrane glucose s ensor that regulates glucose t ransport; has 12 predicted tra nsmembrane segments; long cyto plasmic C-terminal tail is req uired for low glucose inductio n of hexose transporter genes HXT2 and HXT4"
WormBase	Y51A2D.4	9.99510677721488e-07	WBGene00013073 Sugar (and othe r) transporters

General Information

Paragraph No Gene Name Paragraph Text
27 GTP4 GTP4 has only one known functional domain and is a member of the sugar transporter family, a subset of the major facilitator superfamily (E-value: 5.4e-36). This protein appears to be responsible for transporting sugar across the plasma membrane in response to changes in the electrochemical gradient, specifically in sugar uptake. Paragraph by: Kathleen Beardsworth and Kristen Keller (undergraduates), Keck Science Department, Claremont Colleges.

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00188500(coding)
ATGGATATCACAACTGAAGATGGCTAAAAATCTTCTAAAAAATAGGAAGAATAGGAATAT
ATATCGTTTTTGTATATATTAATTAATGTAATTGTTTCGAATCTAGGAATTTTATATTTT
GGATACCACCTCTCAGTTATGTCTTTAGCTTAAGATACCGTTTTTACTGTATTTGAAGTT
AAAGAAAGTTAACATAACTTCTACTCTTCTCTTCTTGCTGCTGCTATTCCTTTTGGAGCT
ATATTTGGAGCAATCATACCTGGTAGCTTTCTTTCTAATAGCTCCAGAAAAAACTCTATG
ATTTTTGCTGATGCTATTGGAACCATTTTTGGACTCTTAGTCTTAACTCGTGATATAAAT
ATGCTTGTTTTAGCAAGACTATGTGCAGGATTTGTCATAGGACTAAATAGCTCACTTGTT
CTTAAATATGTAAATGAAATTACTCCAATTAGTTTAACAGGAGTTATGGGTATAGTCTTT
AGTATATCTTTGACTTTAGGTATAGTTATAGCAAGTTTAAATGGATAGTTTTTTAGTCAA
AATCCTTCTTAAGAAGATTAATACTGCTTTTTTGTACTATTATTTCCATTAATATTTACT
ATTAGCCGTCCTATCTTATTTTAAGTTTTCTTCAATCACGAAACTCCTTTTTATTACATC
CTTAACAACCAACCTGATAGCTGCAAATAATTACTACAAATATTATATAAATCTCAATAT
GTTGACAAAATACTTTTAGAAGTTTAGTAAGAAGTAATTAAGCAAGGCAGCAAAGACACT
TCCAAGAGTTATAATATTAAGCGCTTGTTCATAGGATGTACCTTGCTAATATTTTAGTAG
TTTTCTGGAATAAATGCAGTTATTATGTTTTTAGGTTAAATATTTTAAAAAGAACATTTT
TCATTTAGAATGACAAATTTACTTTCACTACTTTCTAATTTTATTTACTTAATAGCCTCA
ATTCTTAGTACCTGTTACTTTGTTGCCTTCAACTTTTCTCTTGGCCCTGTCATTTGGTTA
TATAGTTCAGAAATTCTTTCATCTAAAGAATTTAGCATAGCTACAACATTGAACTGGATA
AGTGCAACAATAGTAGTTGTTTCAATACCATATTTTGATCATTTGTGGCCACTATTCATT
TTTTTCTCTGTTGTTTGCTTTTCTTGTGCAACCTTCACTTTATTCTTGGTTAAAGAAACT
AAAGATAAAAGCAAATTAGAGATACTTCATTTATATGATCCTTAACAAAAAGATCAAGGT
GAGTATTCTAGTATTGCTTTAAACACTTCTGATCAAAAAAATTACGTAGACTGA

>TTHERM_00188500(protein)
MDITTEDGQKSSKKQEEQEYISFLYILINVIVSNLGILYFGYHLSVMSLAQDTVFTVFEV
KESQHNFYSSLLAAAIPFGAIFGAIIPGSFLSNSSRKNSMIFADAIGTIFGLLVLTRDIN
MLVLARLCAGFVIGLNSSLVLKYVNEITPISLTGVMGIVFSISLTLGIVIASLNGQFFSQ
NPSQEDQYCFFVLLFPLIFTISRPILFQVFFNHETPFYYILNNQPDSCKQLLQILYKSQY
VDKILLEVQQEVIKQGSKDTSKSYNIKRLFIGCTLLIFQQFSGINAVIMFLGQIFQKEHF
SFRMTNLLSLLSNFIYLIASILSTCYFVAFNFSLGPVIWLYSSEILSSKEFSIATTLNWI
SATIVVVSIPYFDHLWPLFIFFSVVCFSCATFTLFLVKETKDKSKLEILHLYDPQQKDQG
EYSSIALNTSDQKNYVD

>TTHERM_00188500(gene)
ATGGATATCACAACTGAAGATGGCTAAAAATCTTCTAAAAAATAGGAAGAATAGGAATAT
ATATCGTTTTTGTATATATTAATTAATGTAATTGTTTCGAATCTAGGAATTTTATATTTT
GGATACCACCTCTCAGTTATGTCTTTAGCTTAAGATACCGTTTTTACTGTATTTGAAGTT
AAAGAAAGTTAACATAACTTCTACTCTTCTCTTCTTGCTGCTGCTATTCCTTTTGGAGCT
ATATTTGGAGCAATCATACCTGGTAGCTTTCTTTCTAATAGCTCCAGAAAAAACTCTATG
ATTTTTGCTGATGCTATTGGAACCATTTTTGGACTCTTAGTCTTAACTCGTGATATAAAT
ATGCTTGTTTTAGCAAGACTATGTGCAGGATTTGTCATAGGACTAAATAGCTCACTTGTT
CTTAAATATGTAAATGAAATTACTCCAATTAGTTTAACAGGAGTTATGGGTATAGTCTTT
AGTATATCTTTGACTTTAGGTATAGTTATAGCAAGTTTAAATGGATAGTTTTTTAGTCAA
AATCCTTCTTAAGAAGATTAATACTGCTTTTTTGTACTATTATTTCCATTAATATTTACT
ATTAGCCGTCCTATCTTATTTTAAGTTTTCTTCAATCACGAAACTCCTTTTTATTACATC
CTTAACAACCAACCTGATAGCTGCAAATAATTACTACAAATATTATATAAATCTCAATAT
GTTGACAAAATACTTTTAGAAGTTTAGTAAGAAGTAATTAAGCAAGGCAGCAAAGACACT
TCCAAGAGTTATAATATTAAGCGCTTGTTCATAGGATGTACCTTGCTAATATTTTAGTAG
TTTTCTGGAATAAATGCAGTTATTATGTTTTTAGGTTAAATATTTTAAAAAGAACATTTT
TCATTTAGAATGACAAATTTACTTTCACTACTTTCTAATTTTATTTACTTAATAGCCTCA
ATTCTTAGTACGTACTTTGTAAAAAAGTATACAAGGAGAGCCATTCTTATAACAGGTTCT
TCATTTGCTGGAATATTTCTGCTCCTATTAGCTCTTTTATAAATTATTGACATATAATAA
ATTTCTTTTCTTGCATTTTTTTTTATTAGCTGTTACTTTGTTGCCTTCAACTTTTCTCTT
GGCCCTGTCATTTGGTTATATAGTTCAGAAATTCTTTCATCTAAAGAATTTAGCATAGCT
ACAACATTGAACTGGATAAGTGCAACAATAGTAGTTGTTTCAATACCATATTTTGATCAT
TTGTGGCCACTATTCATTTTTTTCTCTGTTGTTTGCTTTTCTTGTGCAACCTTCACTTTA
TTCTTGGTTAAAGAAACTAAAGATAAAAGCAAATTAGAGATACTTCATTTATATGATCCT
TAACAAAAAGATCAAGGTGAGTATTCTAGTATTGCTTTAAACACTTCTGATCAAAAAAAT
TACGTAGACTGA

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Identifiers and Description

Gene Model Identifier

Standard Name

Aliases

Description

Genome Browser v.2008 (current)

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

Domains

Gene Expression Profile

Homologs (v.2006 protein sequences)

General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

Wiki Links

External Links

Paragraph No	Gene Name	Paragraph Text
27	GTP4	GTP4 has only one known functional domain and is a member of the sugar transporter family, a subset of the major facilitator superfamily (E-value: 5.4e-36). This protein appears to be responsible for transporting sugar across the plasma membrane in response to changes in the electrochemical gradient, specifically in sugar uptake. Paragraph by: Kathleen Beardsworth and Kristen Keller (undergraduates), Keck Science Department, Claremont Colleges.